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The following medicines should not be combined with generic eldepryl selegiline .

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This medication may increase serotonin and rarely cause a very serious condition called serotonin syndromeThe risk increases if you are also taking other drugs that increase serotoninso tell your doctor or pharmacist of all the drugs you takeGet medical help right away if you develop some of the following symptomshallucinationsunusual restlessnessloss of coordinationfast heartbeatsevere dizzinessunexplained feversevere nausea/vomiting/diarrheatwitching muscle.

Parkinson’s disease patients treated with dopamine agonists and other dopaminergic treatments have been reported as exhibiting impulse control disorders and compulsions like pathological gamblingincreased libidohypersexualitybinge eatingshopping and different kinds of compulsive/repetitive activitiespundingThese may also be possible with selegiline but very few cases have been reported to date.

Studies have related the risk of an increased hypotensive response to concomitant administration of selegiline and levodopain patients with cardiovascular risk.

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